D.M. (Clinical Haematology)

Sem. I

Sr. No.

Subject of Study

A

Core Topics

1. Introduction to clinical haematology
2. Introduction to Laboratory haematology
3. Allied speciality

B

Subtopics

1. Basic morphology and basic concepts of haematopoiesis
2. Bone marrow structure and examination
3. Red blood cells: Structure and function
4. Laboratory approach to the diagnosis of anaemia
5. Development of Immune system
6. Overview of normal haemostatic mechanism
7. Laboratory approach to the diagnosis of bleeding disorders
8. Clinical evaluation and management of inherited bleeding disorders
9. Laboratory approach to the diagnosis of leukaemia
10. Laboratory methods in haematology
11. Principles of Nuclear Medicine: and applications in haematology & oncology
12. Biostatistics

Sem. II

A

Core Topic: Disorders of Erythrocytes: (Part I)

B

Subtopics

1. Iron metabolism and iron deficiency anaemia
2. Megaloblastic anaemia
3. Red cell membrane defect: hereditary spherocytosis
4. Red cell enzymopathies
5. Thalassemia: (a) Clinical aspects and community screening (b) molecular genetics
6. Sickle cell anaemia
7. Abnormal haemoglobins
8. Immune haemolytic anomies

Sem. III

A

Core topic: Disorders of white cells (Part I)

B

Subtopics

1. Cell Cycle and Carcinogenesis
2. Principles of chemotherapy
3. A quantitative defect of neutrophils
4. Reactive lymphocytosis
5. Introduction to acute leukaemia
6. Immunophenotype of acute leukaemia
7. Cytogenetic of acute leukaemia
8. Acute lymphoblastic leukaemia in children
9. Acute lymphoblastic leukaemia in adults
10. Acute myeloid leukaemia
11. Acute promyelocytic leukaemia
12. Minimal residual disease in acute leukaemia
13. MDR genes in Leukaemia
14. Chronic myeloid leukaemia
15. Chronic lymphocytic leukaemia
16. Hairy cell leukaemia
17. T cell lymph proliferative disorders
18. Bone marrow transplantation
19. Disorders of spleen

Sem. IV

A

Core Topics: Disorders of Haemostasis and Thrombosis

B

Subtopics

1. Laboratory diagnosis of platelet function defects
2. Overview of megakaryopoiesis
3. Quantitative platelet disorders
4. Qualitative platelet disorders
5. ITP
6. TTP/HUS
7. Haemophilia
8. Von Will Brand’s disease
9. Dysfibrinogemias
10. Other rare coagulation disorders
11. Fibrinolysis and defects of the fibrinolytic pathway
12. Disseminated intravascular coagulation
13. Lupus anticoagulant
14. Acquired disorders of coagulation
15. Haemostasis in the Newborn
16. Bleeding disorders in the Newborn

Sem. V

A

Core Topic

1. Disorders of haemostasis and thrombosis
2. Disorders of erythrocytes Part II

B

Subtopics

Part A

1. Path physiology of thrombosis
2. Inherited thrombotic disorders
3. Laboratory testing of prothrombotic state
4. Thrombosis in adults: Management issues
5. Paediatric issues in thrombosis
6. Thrombosis and pregnancy

Part B

1. Bone marrow failure syndrome
2. Haematological manifestation syndrome disease
3. Red cell disorders in pregnancy
4. Red cell disorders in the new-born
5. Polycythemia
6. Infections and haematological problems

Sem. VI

A

Core Topic

1. Disorders of white cells Part II
2. Miscellaneous topics

B

Subtopics

Part A

1. Myelodysplastic syndrome
2. Idiopathic myelofibrosis/essential thrombocythemia
3. Non Hodgkin’s lymphoma
4. Hodgkin disease
5. Plasma cell disorders
6. Histiocytosis

Part B

1. Infections and blood transfusions
2. Complications of blood transfusion
3. The haematological manifestation of HIV
4. Consultative haematology
5. Blood and component therapy
6. Blood safety program